I have a used 2010 havent even owned it a month yet when the guages start to bounce around or just not work door locks locking and unlocking while driving lose of power. I take to a auto parts store to see if they could plug a reader into it but it wont link I also tried my buddies still wouldnt link replaced negative cable checked fuses still nothing.

 

My first guess would be a ground issue, but I am not certain of that. The more I read, the more I am glad I own an old Chevy pickup that has no power locks. windows, ect.

Back when I was a very young man, 4 wheel drive pickups were uncommon and most 2 WD pickups didn't even have air-conditioning, something I do have on my 1998' K-1500.

Pretty sure an OBD II reader won't help in this case, but if it wont link up at all, then there is likely some major issue going on with your 2010 Chevy likely a ECM or BCM issue..