On my 2000 Silverado 1500 with a 5.3 my check engine light is on and when hooking it into code reader it has P0160 & P0300.
I've already replaced the plugs and wires so figuring it to be one of the coils, but on the O2 sensor where is Bank2 Sensor 2 located?

 

Bank 1 is always the bank where cylinder No. 1 is, or in this case, the driver's side (left) bank, and Bank 2 is the opposite (right) bank. After the point where the pipes meet, everything is Bank 1.
Now, counting O2 sensors. One is located by the left manifold, which is Bank 1, Sensor 1 (scanner shows B1-S1). Moving back, the sensor in front of the catalytic converter after the Y-pipe is Bank 1, Sensor 2. After the Y, it's all Bank 1, but we still count the sensor in the manifold as 1. So now the sensor behind the catalytic converter is Bank 1, Sensor 3 (scanner shows B1-S3). On a dual exhaust system, the banks stay 1 and 2 all the way back. For example, on the same truck with dual exhaust ... Bank 1, Sensor 1 is in the left manifold; Bank 2, Sensor 1 is at the right manifold; Bank 1, Sensor 2 is behind the driver's side converter; and Bank 2, Sensor 2 is behind the passenger side converter. If automotive engineers decide to add more O2 sensors, they will continue the numbering in this fashion