SO here is the setup:
I start the truck in the morning and drive to home depot, no issues.
I come back out start it and start to drive then I realize I forgot something in the store.

about 5-10 minutes later I come back out, try to start and not even the interior lighting, hood light, or door open tone are operating. the truck is as if there is
no battery.

a tow truck comes and gives me a jump, fires up no issues.
I drive it home with no issues, even swinging through the drive through window at a burger place. about 5 miles, 15 minutes total worth of driving.

I get home, park it, turn engine off, immediately try to start it back up and here
we go again. no interior lights, wont turnover, no clicking sound, nothing.

here is the kicker... I grab my multimeter and check my battery. 12.5 volts!
what am I missing here!?
..........Just sitting here thinking, I'm gonna go see if maybe the cables aren't making a good connection to the battery.

any ideas wtf is going on?

 

I would check the ground wire, i had a problem like that on a 94 blazer, you'd turn the key and everything would work but once you tried to start it everything shut off like someone disconnected the battery. and after that it wouldn't turn anything on until i disconnected the battery and threw the one in my truck in and it started so i turned it off and tried again but same thing happened. crawled underneath after i got it to start again and saw the ground cable going to the block sparking

 

yep, our suspicions were right.
a connection/ground issue.
I took off the wires from the battery terminals and cleaned.
unscrewed the ground wire from the car, gave it a good sanding to clean the connection.
cleaned the battery teminals. refilled the battery cells with water as long as I was messin with it. they werent too bad.

reconnected everything and "tada"
fired right up.
like a rock!

 

some of the simplest things will cause weird problems. glad you got it fixed