2014 Suburban LTZ 4WD, w 125K+ miles. Fuse #25 keeps blowing and believe issue is either with electrical for TPMS or front driver seat. Do separate wiring harnesses exist for these to attempt to unplug and isolate the issue? Any other suggestions? Appreciate any help or direction.

 

What is the fuse name?
Which fuse block, "Under the Hood" or "Instrument Panel"?

 

 

I'd start by unplugging the seat heaters and the seat motors/controls (the simple stuff first). If you're not voltmeter challenged, you could put the amp-meter across the empty DSM fuse socket and watch the amp readings as you troubleshoot. If you see more than 10-20 amps on the meter, don't leave it connected very long or you'll start smoking wires. A safe way to find shorts would be to connect a 12V light bulb across the empty fuse socket, the brighter the glow, the bigger the short.
You might have a wire chaffing problem that has been getting worse since the fuse use to last longer.

 

Came home from running errands. TPMS alert was on dash, the keyfob to lock and unlock was not working, both front seat heaters stopped working. Changed fuse #25, and everything started working except the seat heaters. Just wondering what the original poster of this thread found out (yes, I know it's been a while but....) I guess a trip to the mechanic is warranted unless someone here has another suggestion.
TIA for any suggestions!